GONORRHOEA – MANAGEMENT (PENICILLIN SUSCEPTIBLE INFECTION)

March 12, 2009, 8:02 am

Penicillin susceptible infection

Amoxycillin sodium 1 g intravenously every 6 hours until oral amoxycillin (500 mg 3 times daily for at least 7 days) can be given. Patients (other than pregnant females) who are sensitive to penicillin can be treated with spectinomycin (see below). Pregnant females should be treated with erythromycin

Penicillin resistant infection (first line treatment where PPNG is endemic) Cefotaxime 0.5 to 1 g intravenously three times daily for at least 10 days or Ceftriaxone 1 g intravenously once daily for 7 days or Spectinomycin 4 g in a single intramuscular dose daily (Dose may be divided between 2 gluteal sites).

Gonococcal conjunctivitis

Untreated gonococcal conjunctivitis in neonates is highly contagious and may rapidly lead to blindness. Systemic antibiotics are required e.g.:

Benzylpenicillin 30 mg/kg intramuscularly every 6 hours for 3 days (for penicillin sensitive infections) or Ceftriaxone 25-50 mg/kg intravenously or intramuscularly daily for 3 days (for PPNG) for 7 days or Spectinomycin 40 mg/kg intramuscularly daily for 3 days (for PPNG).

*48/56/1*